LONDON, UK – Existing adoption rates and commercial success of launched Monoclonal Antibodies (mAbs) for therapeutics have established a strong platform for these products. Broadening the horizontal indications for existing mAbs, expanding the applications of mAbs in new therapeutic areas and developing innovative and faster drug delivery mechanism are the current trends in the mAbs market.

Monoclonal Antibodies (mAbs) are mono-specific high molecular weight complex proteins which are capable of post translational modifications like glycosylation.

They are predominantly used in the treatment of cancer and autoimmune and inflammatory disorders. Other areas include cardiovascular and infectious diseases and organ transplants.

Over 45 mAbs are currently used. Drugs developed for cancer and Rheumatoid Arthritis (RA) account for 75% of the total market.

The European therapeutic monoclonal antibodies market, accounting for approximately 33.1% of the global market, is estimated at $19.01 billion in 2011 and is expected to reach $42.37 billion in 2018 with a CAGR of 12.1%.

“Robust activities and strong product potential across both existing and pipeline products drive M&A activities across the monoclonal antibodies market,” explains Deepika Pramod Chopda, Research Associate at Frost & Sullivan. “The alliances commonly observed include that of Big Pharma acquiring small biotech companies helping growth and development across the biologics industry.”

While a strong product pipeline, premium pricing trends and growing market opportunities and success from existing product line-up drive the mAbs market, high developmental costs, the financing of mAbs therapeutics in public healthcare, alternative treatment options within biologics and competition from biosimilars are all factors impeding the market growth.

Therapeutic Monoclonal Antibibodies market for their innovative and lucrative offerings into the biopharmaceuticals market resulted in a positive revenue growth rate through the economic recession. “Growing demand for improvised therapy allure mAbs against conventional chemical drugs for therapeutics,” concludes Ms Chopda. “Strong pipeline and broadening product segments to ophthalmology, respiratory infections will promote their development.”

Frost & Sullivan recently organised an on-demand analyst briefing entitled “Is Biologics the Answer to Rising Disease Incidence.” The web-conference summarizes Ms Chopda’s findings, identifying the market’s drivers and constraints and looking at the pipeline and R&D developments made within the Monoclonal Antibodies market.

This web-conference will benefit investors from the Big Pharma segment to evaluate the development made by small biotech companies promoting Mergers & Acquisitions and Product/Technology Alliance opportunities. Healthcare/medical professionals, venture capitalists and drug manufacturers looking to widen the knowledge about mAbs are also a suitable audience.

The article Is Biologics the Answer to Rising Disease Incidence? appeared first on The Toonari Post - News, Powered by the People!.

There is nothing that brings a little sparkle to your holiday get together with friends and family more than champagne. In fact, Americans will consume more than one billion glasses of champagne this year, over 40 percent during the holiday season, according to Impact Databank. While champagne will add the sparkle, what you do not want to add are injuries to your holiday festivities.

According to the American Academy of Ophthalmology, the careless handling of champagne is one of the most common causes for holiday-related eye injuries. These injuries are often caused by improperly opening the bottle, as a champagne cork is just under 90 pounds of pressure – three times the pressure inside a car tire. So, before you break open a high-pressured bottle of bubbly, it is important to know the proper technique. By following these simple tips, you can open the champagne bottle like a pro – without injury or spilling.

While the popping of a cork may sound festive and exciting, it tends to waste champagne and can be dangerous. The recommended way to properly open a bottle is to ease the cork out slowly, with the sound of a gentle sigh. In order to celebrate this holiday season without injury (or wasting champagne) follow these five easy steps:

1. Make sure your champagne is chilled and unshaken. Chill the bottle for at least four hours in the refrigerator (a warm bottle is more likely to pop unexpectedly).
2. Remove the foil cap covering the top of the bottle, exposing a wire hood.
3. Undo the wire hood with six half-turns of the knob.
4. Hold the bottle at a 45 degree angle while holding the cork firmly with one hand and the base of the bottle with the other. Be sure to point the bottle away from your guests.
5. Do not twist the cork.  Rather, turn the bottle slowly while letting the cork glide out gently, emitting a gentle sigh.

Note: Never use a corkscrew.  A champagne cork is highly compressed. If a corkscrew is inserted at an angle, you may have an exploding bottle in your hand.

Other Champagne tips:

• Expect six generous glasses from one standard size (750ml) bottle.
• The most popular champagne is Brut – it is medium-dry, light, and crisp.
• There are more than 50 million bubbles in a standard bottle of champagne.
• It is best to serve champagne in tapered champagne flutes, as they highlight the fine stream of bubbles. While short, wide goblets can be used in a pinch, they tend to cause the bubbles to dissipate quickly.
• When transporting champagne, keep the bottles upright. The shaking bottles receive in the car can cause champagne to quickly lose its sparkle after opening.  Upright bottles keep wine movement to a minimum and the bubbles in the wine.
• Crisp and versatile, Brut, Natural, Chardonnay, and Brut Rose are delicious with hors d’oeuvres and rich enough to enjoy with many main courses. Sweet Rose, Extra Dry, and Sweet Cuvee offer a bit of sweetness that works well as an aperitif or paired with dessert.
• Celebrate responsibly.  Don’t drink and drive; take a taxi or have a designated driver do the honors.  The best celebrations are those from which everyone gets home safely.

The article Five Safety Steps for Popping the Cork appeared first on The Toonari Post - News, Powered by the People!.